Plan your next synthesis in seconds
Input any target molecule. Get AI-generated retrosynthetic routes, step-by-step protocols, and automated vendor sourcing — all in one platform.
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Synthesis Sessions
Plan retrosynthesis, generate protocols, and source reagents
Used by research chemists & scientists at
Smarter tools,
faster synthesis.
Research with precision
Enter a SMILES string, draw a structure, or search by name. Rasyn identifies the molecule and prepares it for retrosynthetic analysis instantly.
Dissolve 2.0 g salicylic acid in 5 mL acetic anhydride.
Add 5 drops H₃PO₄. Heat at 85 °C for 15 min...
AI plans the synthesis
Our hybrid model ensemble (RetroTransformer v2 + LLM v6) produces ranked multi-step routes with step-by-step protocols, scored by confidence, safety, and cost.
Source every reagent automatically
PubChem-powered vendor search finds every starting material with stock status across Sigma-Aldrich, Fisher, TCI, and more. One click to purchase.
Meet Arcade — your lab's
institutional memory.
Ask natural-language questions about every experiment, route, dataset, and protocol your team has ever run. Arcade searches your indexed records and answers with citations.
Read the announcementArcade
Ask questions about your experiments, routes, datasets, and lab history. Arcade searches your indexed records and answers with citations.
Arcade searches your indexed lab records and answers with citations.
Features
Built for
real chemistry.
Multi-model AI engine
RetroTransformer v2 (69.7% top-1) and RSGPT v6 LLM run in parallel with 20x SMILES augmentation and a copy/pointer mechanism. Complementary architectures maximize route coverage.
Weigh 2.0 g salicylic acid (14.5 mmol) into a 100 mL round-bottom flask.
Add 5 mL acetic anhydride and 5 drops conc. H₃PO₄.
Heat to 85 °C in water bath for 15 min.
AI-generated protocols
Step-by-step experimental procedures with exact reagent quantities, temperatures, TLC checkpoints, safety warnings, and expected yields — ready to execute in the lab.
21 CFR Part 11 compliance
Hash-linked audit trail, electronic signatures, tamper-evident logging, and full traceability for GxP-regulated environments. Every action is recorded and verifiable.
Developer API
Integrate retrosynthesis
into your workflow.
A single API call returns ranked retrosynthetic routes, step-by-step protocols, and vendor sourcing data. Build retrosynthesis into your ELN, LIMS, or custom application.
{
"smiles": "CC(=O)Oc1ccccc1C(=O)O",
"num_routes": 5,
"beam_width": 10,
"include_protocols": true
}
Response will appear here
Click "Send Request" to run
Ready to accelerate your synthesis?
Start with a free account. Input any target molecule and get AI-generated routes, protocols, and vendor sourcing in seconds.
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